Systematic Review and Meta-analysis of the Effects of Elettaria Cardamomum Supplementation on Glycemic Indices and Anthropometric Measurements

Background: Type ۲ diabetes mellitus (T۲DM) is considered a problem for public health worldwide and cardamom (Elettaria cardamomum) as a spice which contains polyphenolic components may have a beneficial effect on the status of diabetes patients. This systematic review and meta-analysis aims to update the efficacy of cardamom intake on weight reduction and glycemic control. Methods: Electronic databases were searched up to December ۲۰۲۳ to identify eligible articles. Mean differences were pooled using a fixed effects model, and standard methods were used for the assessment of heterogeneity, sensitivity analysis, and publication bias. Results: Totally, eight studies were included in the final analysis. Analysis showed that cardamom intake attenuated serum level of insulin [standard mean difference (SMD): -۰.۶۴, ۹۵% CI: -۰.۸۶ to -۰.۴۳, P<۰.۰۰۱], whereas changes of fasting blood glucose (SMD: -۰.۱۳, ۹۵% CI: -۰.۳۳ to ۰.۰۶), weight (SMD: -۰.۰۱, ۹۵% CI: -۰.۲۳ to ۰.۲۰) and body mass index (SMD: -۰.۰۵, ۹۵% CI: -۰.۰۲ to ۰.۱۱) were not significant. Conclusion: According to the findings of the present meta-analysis, cardamom intake significantly declined serum insulin level but did not have any significant effect on fasting blood glucose, weight, and body mass index.

کلیدواژه ها:

Cardamom ، Anthropometric ، Glycemic ، Meta-analysis.