Antibacterial activity of propolis-loaded β-cyclodextrin/cellulose nanocrystals

Nanocrystals have great potential to be used as improved drug carriers due to their low cost, high biodegradability and biocompatibility. In this research, we report the synthesis of β‑cyclodextrin-functionalized cellulose nanocrystal (β-CD/CNCs) as a carrier material to carry propolis and determination of its antibacterial properties. The β-CD/CNCs were characterized using X-Ray Diffraction (XRD), which revealed a crystal structure for β-CD/CNCs. Then, the antibacterial property of propolis loaded β-CD/CNC were determined. The antibacterial activity was investigated using the disk diffusion method. The obtained results proved that the propolis loaded in β-CD/CNCs showed better antibacterial activity than free propolis.

کلیدواژه ها:

Cellulose nanocrystal ، β‑cyclodextrin ، Propolis ، Antibacterial activity