Enhanced Anticancer Efficacy: Synthesis and Characterization of Paclitaxel-Conjugated Gold Nanoparticles

This study investigates the synthesis and characterization of paclitaxel-conjugated gold nanoparticles, aiming to assess their effect on angiogenesis in breast cancer cell lines. Various analytical techniques, including UV-Vis, FTIR, TEM, DLS, and Zeta potential analysis, were employed to evaluate the physical and structural properties of the complex. Results suggest that conjugation significantly alters paclitaxel's release profile and enhances its biological efficacy, showcasing the promising role of nanotechnology in cancer therapy.

کلیدواژه ها:

Anticancer chemotherapeutic drugs ، Solid tumors ، Nanotechnology ، Gold nanoparticles