Validation of Prognostic Biomarkers in Pancreatic Cancer Through Multi - Dataset Analysis and Pathway Enrichment

Pancreatic cancer remains one of the lethal forms of gastrointestinal cancer, characterized by a low five-year survival rate and challenges in early detection. The disease is often diagnosed at an advanced stage due to the pancreas's anatomical position, making it crucial to understand its risk factors for effective prevention. This study aims to identify sets of prognostic biomarkers from pancreatic cancer genomic data by applying to multiple independent datasets to find sets of genes related to the malignant stage of pancreatic cancer. The research will also involve pathway enrichment analysis to elucidate the biological significance of these biomarkers and their potential roles in tumor progression and therapeutic response.

کلیدواژه ها:

pancreatic cancer ، hub genes ، DEGs ، pathway enrichment analysis