An Electrochemical Sensor Based on SnSe Nanosheets and Ionic Liquids for The Selective Detection of N-acetylcysteine

To detect N-acetylcysteine (N-AC), a voltammetric sensor was developed employing a carbon paste electrode (CPE) modified with SnSe nanosheets (SnSe NSs) and ionic liquids (ILs). Compared to the unmodified CPE, the electrochemical sensor (SnSe NSs/ILs/CPE) exhibited significantly higher current responses for N-AC oxidation. Using linear sweep voltammetry (LSV), cyclic voltammetry (CV), chronoamperometry, and differential pulse voltammetry (DPV), the electrochemical properties of the sensor and the oxidation behavior of N-AC were investigated. With a detection limit (LOD) of ۰.۰۲ µM (S/N = ۳), DPV, a sensitive analytical method for N-AC quantification, showed a linear relationship between N-AC concentration and peak current spanning the range of ۰.۰۵ µM to ۴۸۰.۰ µM. In addition, the sensor demonstrated adequate stability and repeatability. With recovery rates ranging from ۹۱.۴۰% to ۱۰۶.۳۰%, it was effectively used to determine N-AC in actual samples.

کلیدواژه ها:

N-acetylcysteine ، Carbon paste electrode ، SnSe nanosheets ، Ionic Liquids ، Cyclic Voltammetry ، Differential pulse voltammetry