Introduction:Multiple Sclerosis (MS) is a profoundly disabling disease that affects the central nervous system,including the brain and spinal cord. Neurons and central nervous system cells are enveloped and protected by a proteinlipidstructure called myelin sheath. MS is the most common autoimmune chronic disease, in which the individual'simmune system is activated against the myelin sheath of neurons, leading to its destruction (۱).This process, known as demyelination, results in the disruption of communication between the central nervous systemand other parts of the body, preventing signals from reaching their intended destinations (۲). Clinical manifestationsof Multiple Sclerosis are categorized into three groups based on the extent of nerve damage: primary symptomsresulting directly from central nervous system demyelination, including weakness, fatigue, tremors, pain, paralysis,bladder and bowel dysfunction, muscle spasms, visual changes, and diminished sexual function in males (presentingas reduced libido) (۳). Secondary symptoms, which are consequences of central nervous system damage, include sleepdisturbances, reduced daily life activities, urinary tract infections, urinary and fecal incontinence, skin problems,muscle contractions, and peripheral neurological issues. Finally, the third category of symptoms (resulting fromprimary and secondary symptoms) encompasses loss of employment, changing roles within the family, divorce, lossof ability to perform financial, social, occupational, and environmental activities, ultimately leading to disability (۳).Method:Our research is a review of the research done in this case, which has been used from Google Scholar,Scopus, PubMed, etc. sites.Conclusion:Based on the results of this study, which indicate the significant impact of balance and independence indaily activities on quality of life, it seems imperative to incorporate balance rehabilitation and training in daily lifeactivities into the treatment plan in order to enhance the quality of life for individuals with MS. One limitation ofthis research is the relatively small sample size, which prevented us from comparing the male and female groups.
