Evaluating drug Susceptibility of fungal species isolated from caught ants in Babol teaching Hospitals

Considering the role of ants as potential carriers of a wide range of fungal agents, including Aspergillus spp. and Candida spp. as well as the increasing incidence of treatment-resistant hospital fungal infections, the antifungal susceptibility of fungal isolated from the surfaces of ants caught from teaching hospitals of Babol city were evaluated. In the present experimental study, ۴۶ fungal isolates including ۱۵ strains of Aspergillus niger, ۱۵ strains of Aspergillus flavus, ۱۱ strains of Aspergillus fumigatus and ۵ strains of Penicillium spp. were cultured on PDA medium and drug susceptibility to psoconazole, isavoconazole, itraconazole, loliconazole and voriconazole was determined according to CLSI (M۲۳۸-A۲) guidelines. The best antifungal effect was related to loliconazole, itraconazole and isaconazole on isolates of Aspergillus niger, Aspergillus fumigatus and Aspergillus flavus, respectively and posaconazole showed the weakest antifungal effect against to the studied isolates. Our knowledge regarding the level of sensitivity or resistance of fungal species with the source of hospital ants can highlight the role of these insects as carriers of hospital infections and also demonstrate the need for a regular preventive programmer to control these insects in different hospitalized areas.

کلیدواژه ها:

Ant ، Antifungal ، Babol ، Aspergillus ، Fungi