Nanotechnology in Tissue Engineering: Enhancing Scaffold Properties for Regenerative Medicine – A Review

سال انتشار: 1403
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 226

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SDNCONF13_001

تاریخ نمایه سازی: 23 آبان 1403

چکیده مقاله:

This document explores the transformative role of nanoparticles in tissue engineering, highlighting their potential to enhance scaffold properties and support tissue regeneration. By integrating nanotechnology, researchers can develop biomaterials that mimic the extracellular matrix, providing a conducive environment for cell growth and differentiation. Key nanoparticles, such as graphene oxide and gold nanoparticles, are examined for their unique physicochemical properties, which improve mechanical strength, biocompatibility, and bioactivity of scaffolds. The document discusses various in vivo and in vitro studies that demonstrate the effectiveness of nanoengineered scaffolds in promoting cellular activities, such as adhesion, proliferation, and tissue integration. Additionally, it addresses the challenges associated with assessing the long-term safety and toxicity of these materials, emphasizing the need for comprehensive evaluations. Advanced imaging techniques, including Scanning Electron Microscopy (SEM), are highlighted as essential tools for understanding the interactions at the nanoscale. Overall, the findings underscore the potential of nanoparticles to revolutionize tissue engineering and regenerative medicine, paving the way for innovative therapeutic strategies and improved clinical outcomes. Continued research and interdisciplinary collaboration are vital for advancing this promising field

نویسندگان

Goolia Nikravan

Caspian Faculty of Engineering, College of Engineering, University of Tehran, P. O. Box: ۱۱۹-۴۳۸۴۱, Rezvanshahr, Iran

Alireza Ramezani

Caspian Faculty of Engineering, College of Engineering, University of Tehran, P. O. Box: ۱۱۹-۴۳۸۴۱, Rezvanshahr, Iran

Hourieh Emadi

Department of Chemical Engineering, Isfahan University of Technology, ۸۴۱۵۶-۸۳۱۱۱, Esfahan, Iran