Comprehensive Review of Medicinal Plants with Anti-Tuberculosis Properties

Tuberculosis (TB) is a severe infectious disease caused by Mycobacterium tuberculosis (MTB) and remains a significant global health issue. The primary challenge in eradicating TB is the development of MTB resistance to existing antibiotics and extended treatment regimens, placing a heavy burden on healthcare systems. Consequently, there is an urgent need to discover new, effective treatments with fewer side effects. Traditional medicines from offer a wealth of medicinal plants and plant-based compounds that present a promising alternative for treating various diseases. While there is substantial research on the biotherapeutic potential of natural compounds for different diseases, TB research has lagged behind. Plant-based compounds, or phytoproducts, are being explored as potential anti-mycobacterial agents that either reduce bacterial load or modulate the immune system, thereby reducing side effects. The effectiveness of these phytochemicals is being assessed through drug delivery using nanoformulations. This review highlights the importance of plant-derived anti-TB compounds and summarizes current research on medical plants with potential anti-mycobacterial activity against MTB.

کلیدواژه ها:

Tuberculosis ، Mycobacterium tuberculosis ، medical plants