Study of Lactobacillus Strain L۲۸ Using Bioinformatics Methods

سال انتشار: 1402
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 95

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شناسه ملی سند علمی:

IBIS12_128

تاریخ نمایه سازی: 12 آبان 1403

چکیده مقاله:

The study of Lactobacillus strain L۲۸ utilizing bioinformatics methods has provided valuableinsights into its genetic and metabolic characteristics, shedding light on its potential applications invarious domains [۱]. highlighted that the comprehensive genomic analysis of Lactobacillus strain L۲۸revealed over ۱۰۰ genes in the Lactobacillus core genome (LCG), which displayed conservedorganization and control, suggesting a common ancestry beyond the Lactobacillus group. This studyidentified genes associated with specific signaling to the host and conserved regulatory systems,indicating a fundamental network of environmental responses present in all Lactobacillus genomes.Furthermore, the presence of the FbpA gene in all sequenced Lactobacillus genomes was emphasized,underlining its potential significance. The study underscored the importance of complete genomesequences for detailed genomic comparisons and provided a platform for analyzing the pan genome,niche-specific genes, and specific features of conserved genes in Lactobacillus genomes. The insightsgained from this study have significant implications for potential applications of Lactobacillus strainL۲۸ in biopreservation, probiotic formulations, and biotechnological applications. This researchexemplifies the pivotal role of bioinformatics methods in unraveling the potential of probioticmicroorganisms for diverse industrial and health-related purposes.

نویسندگان

Zahra Farkhondeh Khoy Fard

Department of Microbiology, Kish International Branch of Islamic Azad University, Kish, Iran

Asal Roane Ghanadzadeh

Department of Microbiology, Kish International Branch of Islamic Azad University, Kish, Iran

Milad Shaghaghy ranjbar

Microbiology Lecturer at Shirin Asal University of Applied Sciences, Tabriz, Iran