Polycaprolactone-Grafted Chitosan-Based Electrospun Shape MemoryPolyurethane Nanofibers

Herein, chitosan nanoparticles (CNPs) were synthesized through the ionic gelation method and then,modified by polycaprolactone (PCL) chains to obtain PCL-grafted CNPs. Shape memorypolyurethane (SMPU) was synthesized via a two-step pre-polymerization procedure. PCL-graftedCNPs/SMPU nanocomposites were prepared by solution casting method using differentconcentrations of NPs. The electrospinning method was utilized to prepare electrospun scaffolds ofthe prepared samples. The effect of PCL-grafted CNPs on the phase separation, thermal, and shapememory properties of the nanocomposites were evaluated. Moreover, the morphology and bioactivityof the electrospun nanofibers were studied. The prepared electrospun shape memory nanofibrousscaffolds show high potential for advanced and smart shape memory-assisted wound-healingapplications.

کلیدواژه ها:

Smart and functional polymers ، polyurethane ، chitosan nanoparticles ، shape memory ، electrospinning.