Comparison of the Effect of ۵ and ۱۰% Intranasal Lidocaine Spray on Improving Headache in Patients with Head Trauma Referring to the Emergency Department

Background & Objective: Headache is a common complaint among traumatic patients referring to the emergency department.  To improve headache in these patients, an effective, fast-acting, accessible and inexpensive drug without a significant effect on the level of consciousness and vital signs is highly needed.    Materials & Methods:  In this double-blind randomized clinical trial (RCT) on patients with head trauma, Group A was given ۵% intranasal lidocaine spray while group B was prescribed ۱۰% intranasal lidocaine spray to improve headache. Headache severity was checked based on numeric pain scale (NPS) before drug administration and then at ۵, ۱۵, ۳۰ minutes and plus ۱ hour post-drug administration, along with patient satisfaction and possible side effects. Finally, the obtained data were analyzed using SPSS ۲۳ software. Results: According to the data, the maximum reduction in headache occurred ۵ minutes after the drug administration. There was a significant difference between the two groups in terms of satisfaction (P value = ۰.۰۲۲), where group A had ۱۰۰% high satisfaction while group B had ۸۷.۵% high satisfaction and ۱۲.۵% ​​had moderate satisfaction. Of the ۸۰ patients in the study, ۳ patients had tearing complications after medication administration, which resolved after ۵ minutes, and one case had nasal mucosal anesthesia, which improved after ۱۵ minutes.   Conclusion: According to the results of this study, the use of ۵% intranasal lidocaine spray is as effective as ۱۰% intranasal lidocaine spray in relieving headache in traumatic patients and was associated with greater satisfaction and fewer complications.