Increasing the catalytic property of tributylhexadecylphosphonium bromide through the displacement of anions and comparing its catalytic activity in the synthesis of some organic compounds

In this study, the combination of tributylhexadecylphosphonium bromide (TBHDPB) was chosen as an effective catalyst in the one-pot synthesis of ۳, ۴-dihydropyrimidinone (thione). This compound was reacted with potassium peroxypersulfate and persulfate anion (S۲O۸۲-) was introduced instead of bromide ion in tributylhexadecylphosphonium bromide compound and tributylhexadecylphosphonium peroxypersulfate compound was formed with two sites to activate the reactants. It was used in the synthesis of dihydropyrimidinones and imidazoles. It was found that the catalytic activity of tertylhexadecylphosphonium bromide was improved through the replacement of Br- bromide anion with K۲S۲O۸ anion.The mentioned catalysts accelerated the synthesis of dihydropyrimidinone derivatives and imidazoles through condensation reactions and cyclization of compounds related to synthesis at appropriate temperature. The low cost and accessibility of the catalyst, the simplicity of the method of use, the mild reaction conditions are the important advantages of this research.The obtained compounds were identified by FT-IR, ۱HNMR and ۱۳CNMR spectroscopy as well as melting point measurement and comparison with the reported compounds.

کلیدواژه ها:

Tributyl hexadecyl phosphonium persulfate ، dihydropyrimidinone (thion) ، Imidazole