Aptamer-Based Approaches in Oncology
محل انتشار: فصلنامه پزشکی شخصی، دوره: 9، شماره: 34
سال انتشار: 1403
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 20
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شناسه ملی سند علمی:
JR_PMJ-9-34_002
تاریخ نمایه سازی: 6 شهریور 1403
چکیده مقاله:
Cancer is a significant global cause of mortality, and enhancing therapy is essential to save lives and minimise adverse consequences. Aptamers, composed of DNA or RNA, have the potential for cancer treatment by precise targeting of certain molecules. Aptamers, unlike conventional therapies such as chemotherapy, have the specific objective of delivering medications directly to cancer cells, while reducing injury to healthy cells. This paper examines the process of aptamer development and utilisation in cancer treatment, with a specific emphasis on their capacity to enhance therapy and surmount drug resistance. Additionally, it explores the obstacles and potential advancements in using aptamers to transform cancer therapy.
نویسندگان
Behnoush Khashii
Department of pathobiology, faculty of veterinary science, Bu Ali Sina university, Hamedan, Iran
Parisa Haghpour
Department of Biotechnology, Alzahra Universit, Tehran, Iran