A green one-pot, three-component reaction of isatin, thioglycolic acid and amines catalyzed by citric acid at room temperature

A convenient procedure for synthesis of medicinally important spiro[indole-thiazolidinone] derivatives has been developed by one-pot condensation reaction of isatin, thioglycolic acid and amines using citric acid as a catalyst at room temperature

کلیدواژه ها:

Citric acid ، Spiro[indole-thiazolidinone] ، Isatin ، Thioglycolic acid ، Three-component