One-pot tandem reaction of N-methyl barbituric acid with aldehydes in the presence ofcyanogen bromide and N-methyl morpholine

One-pot tandem reaction of unsymmetrical ۱-methy barbituric acid (۱-MBA), BrCN, variousdialdehydes in the presence of N-methyl morpholine afforded diastereomeric mixtures of a series of stable Nmethylmorpholinium bis-(۱-methyl barbiturates) containing charge-separated intermolecular and eightmembered intramolecular H-bonds.

کلیدواژه ها:

۱-methy barbituric acid ، N-methyl morpholinium salt ، bis-(۱-methyl barbiturates)