Synthesis of new derivatives of ethyl ۲-hydroxycinnamate based on ۲-hydroxy-۵-(۲,۴,۵-triphenyl-۱H-imidazol-۱-yl)benzaldehyde

In this research, ethyl ۲-hydroxycinnamate derivatives were synthesized during several reaction steps.First, tetraarylimidazole derivatives were prepared through a multicomponent reaction. Next, their orthoformylationwas done using hexamethylenetetramine via Duff reaction. After that, ethyl trans-۲-hydroxycinnamateswere synthesized through Wittig reaction between synthetic salicylaldehyde compounds, and theethyl bromoacetate

کلیدواژه ها:

Ethyl ۲-hydroxycinnamate ، Duff reaction ، Wittig reaction ، Salicylaldehyde