Synthesis of Functionalized Benzothiadiazine ۱,۱-dioxide Derivatives via the Reactions ofBenzenesulfonylchloride and Trichloroacetamidine

In this study, the synthesis of functionalized benzothiadiazine ۱,۱-dioxide derivatives was achievedthrough a novel three-component intramolecular C-H activation reactions from benzenesulfonylchloride,trichloroacetonitrile and various primary amines. This reaction was performed in the presence of catalyticamount of copper (I) and L-proline as the ligand in tetrahydrofuran at room temperature

کلیدواژه ها:

C-H Activation ، Benzothiadiazine ۱ ، ۱-dioxide ، Benzenesulfonylchloride ، Trichloroacetonitrile