Preparation and Characterization of Β-Cyclodextrin Dialdehyde as a Drug Carrier

Curcumin, as a naturally occurring polyphenol, has been extensively used as anticancer and antioxidantagent due to its ability to protect cells from oxidative damage. β-cyclodextrin(β-CD) was oxidized by sodiumperiodate to yield a mixture of dialdehyde oligosaccharides. Curcumin loading was carried out in betacyclodextrindialdehyde with antioxidant properties and All observations using FT-IR, NMR, UV-Vis and FE-SEMconfirmed successful preparation of the CUR@DA-β-CD.

کلیدواژه ها:

β-Cyclodextrin ، sodium periodate ، curcumin ، host-guest.