Three-component reaction of Isoquinoline and acetylenic esters in the presence ofphenylthiourea derivatives

An efficient and one-pot method is described for the yliden acetate derivatives via simple reaction ofdialkylacetylenedicarboxylate and phenylthiourea derivatives in the presence of isoquinoline, promotedcomponent, under solvent-free conditions. The good yields of the products are synthetic advantage of thisenvironmentally friendly method.

کلیدواژه ها:

Isoquinoline ، Phenylthiourea ، Thiazolan ، Green Chemistry ، Benzyl Phenylthiourea ، Yliden Acetates.