One-pot synthesis of pyridopyrimidines via reaction of enaminones or uracils with in situgenerated Chalcones

A one-pot reaction is presented for the synthesis of pyridopyrimidine and quinoline derivatives, whichare nitrogen-containing heterocyclic compounds with various medicinal properties. Chalcone derivatives aregenerated in situ from the reaction of aldehyde and ketone derivatives, then trapped by enaminone or uracil toproduce the corresponding pyrido[۲,۳-d] pyrimidine and quinoline derivatives

کلیدواژه ها:

Pyridopyrimidine ، Quinoline ، Chalcone ، Enaminone ، Uracil