A one-pot four-component approach to synthesis of novel spiro[acenaphthylene-۱,۴'-chromene]-۳'-carbonitrile and spiro[acenaphthylene-۱,۱'-pyrano[۲,۳-c]chromene]-۲'-carboxylate derivatives

An efficient one-pot four-component condensation reaction of acenaphthoquinone, malononitrilederivatives or ۲-cyanoacetamide and triazolamino-chromen-۲-one and triazolamino-dimethylcyclohex-۲-en-۱-one in ethanol for the combinatorial synthesis of novel spiro[acenaphthylene-۱,۴'-chromene]-۳'-carbonitrileand spiro[acenaphthylene-۱,۱'-pyrano[۲,۳-c]chromene]-۲'-carboxylate derivatives has been achieved. Thesignificant features of this reaction include, short reaction time, no column chromatographic purification,excellent yield, avoidance of environmentally hazardous solvents and catalyst-free condition, operationalsimplicity and readily available starting materials

کلیدواژه ها:

Acenaphthenequinone ، Spiroacenaphthoquinone ، ۳-Amino-۱ ، ۲ ، ۴-triazole ، Dimedone