Onion Extract (Allium Cepa L.): A Green and Eco-friendly Catalyst for the MW-AssistedSolvent-Free Synthesis of ۵-Substituted ۱H-Tetrazoles

۵-Substituted-۱H-tetrazoles can be synthesized from the corresponding nitriles by reaction with NaN۳ usingthe efficient and green onion extract catalyst under microwave irradiation and solvent- free conditions in good toexcellent yields (up to ۹۸%) and very short reaction times. This method is applicable to a wide range of aryl and alkylnitriles with sodium azide in solvent-free media, and affords the various tetrazole derivatives in an eco-friendlysolvent-less procedure under microwave irradiation at reaction temperature ۱۲۰ °C. The use of onion extract makesthe process environmentally benign.

کلیدواژه ها:

Microwave ، Onion extract ، Tetrazole ، Eco-friendly