Aryl sulfonyl hydrazide-Induced ۱,۶-Enyne Radical Cyclization under Copper Catalysis:Access to ۳,۴-Dihydronaphthalen-۱(۲H)-one Derivatives

We describe a fascinating approach to access ۴-aroyl-۳-aryl-۳,۴-dihydronaphthalen-۱(۲H)-onederivatives with moderate to good yields through the Cu-catalyzed radical cyclization/desulfonylation of ۱,۶-enynes with aryl sulfonyl hydrazide under air conditions. Significantly, this protocol involves an approach thatworks under mild reaction conditions and external oxidant free and represents an alternative and sustainablestrategy for desulfonylation

کلیدواژه ها:

۱ ، n-Enynes ، Aryl sulfonyl hydrazide ، Radical cyclization