Phosphoramido Acid Derivatives: QSAR Study of Anti-Urease Activity and DFT Calculation

New derivatives of phosphoramido acid were synthesized and in each of these compounds, the Patom was in a tetrahedral environment. (QSAR) was used to understand the relationship between molecularstructural features and inhibitory. Results demonstrated the importance of QH parameter in describing theanti–urease activities of phosphoramido acids including P(O)-NH۲ moiety

کلیدواژه ها:

phosphoramido acid ، urease inhibitor ، QSAR