Cancer Immunotherapy Using Microfluidic Systems

سال انتشار: 1403
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 82

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شناسه ملی سند علمی:

JR_PMJ-9-33_001

تاریخ نمایه سازی: 29 خرداد 1403

چکیده مقاله:

Physicians are enthusiastic about using a novel approach known as cancer immunotherapy to address various forms of cancer. However, there are occasions when novel therapies that demonstrate efficacy in laboratory settings may not provide the same level of effectiveness when applied to actual patients. To address this issue, scientists are using miniature replicas known as microfluidic models. These models provide the examination of the interaction between cancer and immune cells in a manner that closely resembles the physiological conditions inside the human body. This review examines the role of microfluidic models in advancing the development of more effective cancer therapies. Let's begin by discussing the current state of affairs in cancer immunotherapy. Next, we explore the use of microfluidic models by scientists to gain insights into the mechanisms via which the immune system combats cancer and to evaluate the efficacy of novel therapeutic interventions. Additionally, we discuss the first measures used to demonstrate the efficacy of these models in predicting the effectiveness of therapies in human subjects. Lastly, we will discuss the advantages of using microfluidic models and the necessary steps to enhance their efficacy in the development of novel cancer therapies.

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نویسندگان

Maryam Diansaei

Department of veterinary medicine, Islamic Azad University of Tabriz, Tabriz,Iran.