Comparison of the characteristics of coronavirus disease ۲۰۱۹ (COVID-۱۹) in dead and survived patients with heart failure: A retrospective study from northern Iran

During coronavirus disease ۲۰۱۹ (COVID-۱۹), one of the comorbidities that can cause more severe negative clinical consequences than other patients are heart failure (HF) disease. This study aimed to assess and compare characteristics of COVID-۱۹ in dead or survived patients with HF. Using a retrospective study, ۷۸ HF patients with COVID-۱۹ referred to a heart center in northern Iran were included. Data gathering was performed via census sampling from August ۲۰۲۰ to ۲۰۲۱. The medical records of Hf patients with COVID-۱۹ were assessed. Chi-square and t-tests were used to assess the relationship between study variables. Multiple logistic regression analysis was also applied to assess the relationships of clinical and demographic characteristics with in-hospital mortality. A total of ۷۸ HF patients with COVID-۱۹ were included in this study. The mean EF, duration of HF, and blood pressure of the patients were ۲۵.۸۳ (SD=۱۲.۳۱), ۳.۷۹ (SD=۲.۱۰) years, and ۱۲۶.۶۵ (SD=۲۴.۶۷) mmHg, respectively. Also, ۷۴.۳۶% and ۳۰.۷۷% of patients had hypertension/hypotension and angioplasty, respectively. Finally, ۵۵.۱۳% of HF patients with COVID-۱۹ died. Most of the dead (۶۵.۱۲%) were females but most of the survivors (۶۸.۵۷%) were males (P=۰.۰۰۳). Mean blood pressure of dead patients was lower compared to survived patients (۱۲۱.۲۶ vs. ۱۳۳.۲۷ mmHg; P=۰.۰۳۲). Age and blood pressure were predictors of in-hospital mortality in HF patients with COVID-۱۹. The odds of in-hospital mortality were higher in males compared with females (OR=۳۵.۷۱۷; ۹۵% CI: ۲.۶۷۶ to ۴۷۶.۶۹۰; P=۰.۰۰۷). Also, the odds of in-hospital mortality increased with decreasing blood pressure (OR=۰.۹۴۵; ۹۵% CI: ۰.۹۰۰ to ۰.۹۹۳; P=۰.۰۲۴). Therefore, health managers and policymakers should pay special attention to COVID-۱۹ patients with HF.

کلیدواژه ها:

COVID-۱۹ ، SARS-CoV-۲ ، Heart failure ، mortality ، Cardiovascular Diseases