Frequency of Human papilloma virus among pregnant women by PCR technique

Today, it has been confirmed that the viral infections play an important role in premature delivery and abortion. This study was carried out to determine the frequency rate of papilloma virus types ۱۶ and ۱۸ in pregnant women and their relationship with premature delivery and abortion. In this study, vaginal secretions were collected from pregnant women who had been referred to the women clinics in Tonekabon, a city in North of Iran. The samples were used to amplify E۶ gene of papilloma virus through Polymerase Chain Reaction method. The results were analyzed by χ۲ statistical test. Of ۴۷ tested samples, ۱۴ cases were infected with type ۱۶ papilloma virus (HPV۱۶) (۲۹.۷۸%), while ۳ cases were infected with type ۱۸ papilloma virus (HPV۱۸) (۶.۳۸%). Papilloma virus infection had no significant relationship with abortion and premature delivery. Considering the obtained findings, it appears that a high percentage of the study population was infected with HPV۱۶ virus. Therefore, risk of affliction with abortion and premature delivery can be decreased up to a limit in this region by screening before pregnancy.

کلیدواژه ها:

Human papilloma virus ، premature delivery ، Polymerase Chain Reaction (PCR)