The Chlamydia trachomatis genotypes isolated from women with cervicitis in Kamali Hospital of Karaj (Iran)

BACKGROUND AND OBJECTIVESChlamydia trachomatis is considered to be one of the main pathogens of venereal diseases. There is no data concerning the frequency and genotyping of C. trachomatis in Iranian women who had cervicitis referred to Kamali Hospital of Karaj city and estimate the potential risk factors for this sexually transmitted disease.MATERIALS AND METHODSCervical samples collected from ۲۰۱ women with initial diagnosis of cervicitis (mean age ۲۱.۵ years) were analyzed through molecular assay for the detection of Clamydial infection. Phylogenetic analysis on the ompA gene was performed on positive samples to identify the corresponding genotype.RESULTS AND DISCUSSIONOut of ۲۰۱ samples, ۱۱۴ (۵۶.۷%) samples were C. trachomatis positive. Twentyfive positive samples were sequenced randomly. The genotype L۲ (۲۴ [۹۶ %]), D (۱ [۴%]) were identified. Interestingly, none of the patients who were positive to genovar L۲ had symptoms of lymphogranuloma venereum (LGV).CONCLUSIONIn comparison to similar researches, our results show a higher prevalence of C. trachomatis infection in female patients with cervicitis in Karaj. The findings also emphasize on diagnostic tests for C. trachomatis infection should be included in the screening programs for women.

کلیدواژه ها:

Chlamydia trachomatis ، Cervicitis ، Genotype ، omp۱