Serological survey of H۵, H۷ and H۹ subtypes of Avian Influenza Viruses in human population related to poultry industry

BACKGROUND AND OBJECTIVESInfluenza viruses are an acute respiratory, highly contagious and zoonotic disease which belong to the Orthomyxoviridae family. The H۹ subtype is an avian pathogenic influenza virus that its outbreak frequently occurs in poultry farms of Iran. As well, H۵ and H۷ subtypes are a highly pathogenic avian influenza subtype which causes high mortality in poultry and wild birds. Some subtypes of influenza viruses can transmit to human from birds and the antigenic shift is common among these viruses.MATERIALS AND METHODSThis study was to carried out to determined antibodies to H۵, H۷ and H۹ subtypes of avian influenza virus in different human population related to poultry industry in Ardabil area, northwest of Iran. In this survey, ۱۰۵ blood samples were collected from poultry vaccinators and clinics, and workers of poultry farms and slaughter-house. Serum samples were examined by HI test for differentiate H۵, H۷ and H۹ subtypes and sera with titers ≥۴ (log۲) were considered positive.RESULTS AND DISCUSSION: ۱۷.۲% with ۲۱.۱۴±۱۰.۵۹ titer from poultry vaccinators and clinics sera and ۱۲.۸% with ۲۶.۰۲±۱۱.۳۵ titer from workers of poultry farms and slaughter-house sera were positive for H۹N۲ influenza virus (HI titers ≥۱/۲۰). All tested sera were negative for H۵N۱, H۵N۲, H۷N۱ and H۷N۷ avian influenza viruses.CONCLUSION: According to results of this study, different human population related to poultry industry were contacted with H۹N۲ avian influenza virus that it should be critical during outbreaks of avian influenza subtypes posing a major public threat.

کلیدواژه ها:

Avian influenza viruses ، Human population ، HI test