A Review of human and dog gut microbiome similarities as a new interdisciplinary research approach

BACKGROUND AND OBJECTIVES The gut microbiome includes a set of bacteria, viruses, fungi, and other microorganisms that exist in the gut, and they have a significant impact on food digestion, strengthening the immune system, reducing inflammation, and overall health. The species and genome of the dog gut microbiome have many similarities with the human gut microbiome; Awareness of these similarities can lead to the creation of new approaches to human and dog health. This study aims to review the similarities in human and dog intestinal microbiomes as an interdisciplinary approach.MATERIALS AND METHODS The desired information in this study, by searching indexed articles in GoogleScholar, Science Direct, Pubmed, SID, Magiran, Civilica, and Iranmedex, and also a free search in Google with the keywords; “Gut Microbiome”,” Human” and “Dog” has been obtained.RESULTS AND DISCUSSION The common gut microbiome of humans and dogs are more similar in structure and function. Many bacterial species, including Lactobacillus, and Bacteroides, are similar in the human and dog microbiome; Also, according to studies, human and dog microbiomes have similar gene content. The reason for the similarity of the intestinal microbiome of dogs and humans is that humans and dogs live in a common situation, also, the food that humans and dogs consume is similar, and this makes the bacterial flora in their intestines similar. In addition, the intestines of humans and dogs have many similarities, which makes the bacteria in them similar.CONCLUSION Having a common gut microbiome in humans and dogs can provide information about nutrition, gut health, and even diseases shared by humans and dogs. By studying the common microbiome, we can better understand how the nutrition and living conditions of humans and animals cause changes in the gut bacterial population and how these changes can affect gut health and overall health. By studying the common microbiome, one can look for new solutions to treat some diseases, including inflammatory bowel diseases, diabetes, obesity, and mental disorders in humans, and to treat skin diseases, allergies, and digestive disorders in dogs. Veterinarians and physicians can do joint and interdisciplinary scientific work on the common microbiome between humans and dogs, especially in providing good interdisciplinary colleagues' diets.

کلیدواژه ها:

Gut Microbiome ، Human ، Dog