Investigating the effects of Klebsiella uterine infections on the reproductive rate of mares of Kurd and DerehShoor in Kerman province

BACKGROUND AND ABJECTIVEKlebsiella pneumoniae causes a wide range of infections and the bacterium has the ability to cause infection in almost any organ of the body. The remarkable point is that out of hundreds of antibiotics produced in nature that have been purified, only a limited number are non-toxic and as a result they are used as antibiotics. One of the important characteristics of this bacterium is its low sensitivity to antibiotics. Placental fetal infections cause one-third of horse abortions. Therefore, the aim of this study was to investigate the effects of uterine infections with Klebsiella origin on the reproductive rate of mares of Kurdish breed and DerehShoor of Kerman province.MATERIALS AND METHODSThe current study is a descriptive-cross-sectional type of research that was collected in ۱۴۰۲ from ۴۰ adult horses with clinical symptoms. In this research, among forty adult mares of the DerehShoor (۲۰ head) and Kurd (۲۰ head) breeds, with an average age of five to fifteen years, with amber and brown color, which had a previous pregnancy (۷-۸ foals), for example Respiratory secretions and uterine secretions were used. Antibiogram culture regarding the antibiotic sensitivity of the isolated bacteria was performed based on the CLSI standard. Uterine (vaginal) ultrasound was performed using a ۵.۷ MHz probe and through the mentioned methods: through the abdomen - through the vagina.RESULTS AND DISCUSSIONFor the sensitivity of bacteria isolated from all samples, Mueller Hinton Agar (Merck Company, Germany) was used to check the minimum concentration (dilution) of the inhibitor. The investigated antibiotics included amikacin (AM), Norfloxacin (Nor), the most sensitive, cefixime (CFM), Nalidixic acid (NA), sulfamethoxazole (SXT), the most resistant, and nitrofurantoin (FM۳۰۰).CONCLUSIONAccording to the results of this study, the diagnosis of endometritis after birth and spherogenesis in the clinical environment usually includes examination of the reproductive system within ۴۸ hours after delivery. All mares experience some degree of physiological endometritis, which includes a mechanical or immune response used by the mare to shed excess. Complete treatment with antibiotics is no longer an appropriate strategy and must be evidence-based. The growing interest in non-antibiotic alternatives warrants further investigation, but more data are needed to assess their efficacy and safety.

کلیدواژه ها:

Bacterial contamination ، Klebsiella pneumoniae ، mares ، endometritis ، Antibiogram