Experimental Investigation of Governing Parameters in the Electrospinning of Poly(۳-hydroxybutyrate)-Starch Scaffolds: Structural Characterization
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 79
فایل این مقاله در 9 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JRCC-4-10_002
تاریخ نمایه سازی: 5 اسفند 1402
چکیده مقاله:
In this study, for the first time, electrospinning of polyhydroxybutyrate/starch was done and optimized to produce uniform-size and bead-free nanofibers following Taguchi methodology. The main parameters such as solvent type, applied voltage, flow rate and rotating speed play an essential role in the characteristics of the nanofibrous morphologies. It found out from the main effects that the solvent type (chloroform/dimethylformamide, trifluoroacetic acid) is the most effective factor in the diameter and quality of the fibers. A scanning electron microscope assessed the structure and the average diameter of the fibers. The results indicated that all scaffolds have three-dimensional structures with interconnected porosity. The optimum levels of factors were determined as follows: ۱۸ kV of voltage, ۰.۷۵ µL/h of flow rate, ۱۵ cm of distance, and TFA as solvent in order to obtain the thinnest bead-free nanofibers.In this study, for the first time, electrospinning of polyhydroxybutyrate/starch was done and optimized to produce uniform-size and bead-free nanofibers following Taguchi methodology. The main parameters such as solvent type, applied voltage, flow rate and rotating speed play an essential role in the characteristics of the nanofibrous morphologies. It found out from the main effects that the solvent type (chloroform/dimethylformamide, trifluoroacetic acid) is the most effective factor in the diameter and quality of the fibers. A scanning electron microscope assessed the structure and the average diameter of the fibers. The results indicated that all scaffolds have three-dimensional structures with interconnected porosity. The optimum levels of factors were determined as follows: ۱۸ kV of voltage, ۰.۷۵ µL/h of flow rate, ۱۵ cm of distance, and TFA as solvent in order to obtain the thinnest bead-free nanofibers.
کلیدواژه ها:
نویسندگان
Maryam Abdollahi Asl
Tissue Engineering and Regenerative Medicine Institute, Central Tehran Branch, Islamic Azad University, Tehran ۱۴۶۹۶۶۹۱۹۱, Iran
Mohammad Mohammadalipour
Department of Chemical Engineering, Isfahan University of Technology, Isfahan ۸۴۱۵۶-۸۳۱۱۱, Iran
Saeed Karbasi
Department of Biomaterials and Tissue Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran