تاثیر تزریق نانواکسیدروی بر پاسخ ایمنی، فعالیت آنزیم های اکسیداتیو پلاسما و بیان ژن اینترلوکین بافت طحال در جوجه گوشتی

This experiment was conducted to investigate the effect of zinc oxide nanoparticls injection on immune response and performance in broilers. One hundred eight Ross۳۰۸ strain chicks were injected in a completely randomized design with three treatments in four replicates and nine chicks in each replicate on the day of hatching. The treatments include: ۱. Control, ۲. Injection of ۲۰ microliters of zinc oxide nanoparticls (۰.۵ mg of zinc oxide nanoparticls in ۵۰ ml of saline), ۳. Injection of ۲۰ microliters of zinc oxide nanoparticles (۰.۶ mg of zinc oxide nanoparticles in ۵۰ ml of saline). The zinc oxide nanoparticls solution was injected into the chickens from the neck area. The ration used for all treatments was the standard ration of Ross ۳۰۸ strain. Influenza antibody titer ۱۴ days and CBH test, ۱۲ and ۲۴ hours after vaccination and glutathione peroxidase activity level increased significantly in treatment ۳ compared to other treatments (P<۰.۰۵). Interleukin ۱۲ gene expression in treatment ۲ and ۳ was significantly higher than the control treatment (P<۰.۰۵). The relative weight of gravel in treatment ۳ compared to the control treatment and the feed consumed in treatments ۲ and ۳ were significantly lower than the control treatment (P<۰.۰۵). The results showed that the injection of zinc oxide nanoparticls increased the general and cellular immune response, the activity of antioxidant enzymes and interleukin ۱۲ gene expression.

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اینترلوکین ، آنفلوانزایمرغی ، گلوتاتیونپراکسیداز ، سوپراکسیددیسموتاز