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مقالات فارسیISIکنفرانسهاژورنالها

Comparing the Effect of Grape Fermentative Product and Fresh Red Grape Juice on Antioxidant Biomarkers of Liver Mitochondria Isolated From Rats in Vitro

محل انتشار: مجله تحقیق در پزشکی مولکولی، دوره: 9، شماره: 1
سال انتشار: 1399
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 38

نسخه کامل این مقاله ارائه نشده است و در دسترس نمی باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1881738

شناسه ملی سند علمی:

JR_REMJ-9-1_003

تاریخ نمایه سازی: 20 دی 1402

چکیده مقاله:

Background: Mitochondria are a source of reactive oxygen species (ROS), and several natural compounds are used as antioxidant agents. This study aimed to investigate and compare the effects of fresh grape juice red wine on oxidative stress biomarkers in rat liver mitochondria. Materials and Methods: In this regard, mitochondria were isolated from the liver of ۲۷ male Wistar rats (۲۲۰-۲۵۰ g). The isolated mitochondria were cultured in different doses of red wine and fresh red grape juice for ۲۴, ۴۸, and ۷۲ h. After treatment, total antioxidant capacity, lipid peroxidation, total thiol groups, and catalase activity were determined in the isolated mitochondria of the rat liver. Results: The results confirmed the oxidant/antioxidant effects of red wine and fresh red grape juice at different times. Conclusion: According to the results, the fresh red grape juice showed higher antioxidant properties than red wine in the liver mitochondrial samples.

کلیدواژه ها:

Antioxidant ، Grape juice ، Liver mitochondria ، Red wine

نویسندگان

Amir Keshavarzi

Research Center for Behavioral Disorders and Substances Abuse, Hamadan University of MedicalSciences, Hamadan, Iran.

Akram Ranjbar

Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Nejat Kheiripour

Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.

Ali Ghaleiha

Research Center for Behavioral Disorders and Substances Abuse, Hamadan University of MedicalSciences, Hamadan, Iran.

Alireza Soltaniyan

Department of Epidemiology, Faculty of Health, Hamadan University of Medical Sciences, Hamadan, Iran.

Seyyed Mostafa Hashemi

Research Center for Behavioral Disorders and Substances Abuse, Hamadan University of MedicalSciences, Hamadan, Iran.

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