Investigating antimicrobial effect of Zataria extracts produced by ultrasound on salmonella typhimurium

Introduction: Zataria multiflora is a plant of the Lamias family. The most effective antimicrobial composition is its thymol and carvacrol. Salmonella typhimurium is a genus of Salmonella from the Enterobacteriaceae family. This gram-negative basil, optional aerobic or anaerobic, cause diseases such as inflammation of the intestine, systemic infection, and intestinal fever. The purpose of this study is to investigate antimicrobial effect of Zataria extracts produced by ultrasound on salmonella typhimurium bacteria. Materials and Methods: Salmonella typhimurium was isolated from fecal specimens of poultry in ۱۳۹۴. The Carla plant is placed in an ethanol solvent after collecting and milling and then exposed to ultrasound for ۱ hour. Minimum inhibitory concentration and minimum bactericidal concentration are determined by microdilution method. Results: The results of this study showed that the Zataria extract showed the most inhibitory effect in the concentration of ۰.۶۲ mg / ml and the highest inhibitory concentration was ۱.۲۵ mg / ml. The highest bactericidal concentration was ۲۵ mg / ml. Salmonella typhimurium strains have been resistant to ampicillin antibiotics. Conclusion: It would be possible to treat Salmonella typhimurium infection by developing an appropriate herbal medicine with less side effect. However, ultrasound has increased the antimicrobial activity of the extract of the plant in this study.

کلیدواژه ها:

Ultrasound ، Zataria multiflora ، Antimicrobial activity ، Salmonella Typhimurium