Breast Cancer Survival Rate in Mashhad, Iran: A ۱۰-year population-based study

Introduction: The breast cancer burden is still increasing, both in developing and developed countries. The present study was conducted to determine the survival rate of breast cancer based on tumor biological subtypes in patients referring to three referral oncology centers at Mashhad University of Medical Sciences, Mashhad, Iran.Methods: The present population-based study was conducted at Imam Reza Hospital, Omid Hospital, and Reza Oncology Center, Mashhad University of Medical Sciences, Mashhad, Iran Demographic information, the status of biomarkers in immune-histochemical evaluation, clinical and pathological features of the tumor, type of therapy, recurrence, or death was recorded for each eligible patient.Results: In total, ۲۴۷ patients were included in the study. The mean age of patients was ۴۸.۸ ± ۱.۳ years. The mean time of survival was ۲.۶۴±۰.۱۳ years. In detail, the survival rate from the first year to the fifth year was reported as ۱۰۰%, ۹۶%, ۹۱%, ۹۰%, and ۸۹%, respectively. The survival rate of the luminal B subtype was higher than other subtypes but the difference was not significant (P=۰.۷). Only in terms of metastasis, there was a significant difference between the alive and dead patients (P=۰.۰۰۰۱).Conclusion: Despite no significant relationship between biological markers, the breast cancer subtype, and its survival rate, the overall survival rate of the patients decreased lightly through five years. However, further studies are required to indicate more accurate data about the breast cancer survival rate in our region.

کلیدواژه ها:

Breast Cancer ، Iran ، Survival rate ، Epidemiology