Ultrasound-guided (USG) transversus abdominis plane (TAP) block with bupivacaine and dexmedetomidine on the control in postoperative analgesia of inguinal hernia surgery: A randomized clinical trial

Introduction: Transversus abdominis plane block (TAPB) is now a well established technique in postoperative analgesia for lower abdominal surgeries. We aimed to investigate the effects of adding dexmedetomidine to bupivacaine used in USG (TAP block on postoperative pain and complications in patients undergoing inguinal hernia repair repair. Materials and Methods: About ۶۶ eligible patients enrolled in the survey. They were randomly assigned to one of the two groups of ۲۰ CC of bupivacaine ۰.۵% + ۱ CC Normal saline or ۲۰ CC of bupivacaine ۰.۵% + ۱۰۰µg dexmedetomidine. The amount of pethidine consumption, postoperative VAS score, and complications were measured. Patients were evaluated at the recovery ward (T۰) and ۲, ۴, ۶, ۱۲, and ۲۴ hours after surgery. Regarding the VAS score and if the patient's pain complained from a VAS≥۳, pethidine ۰.۵ mg/kg was administered. The total dose, the average dose of pethidine used, and the first time of pethidine administration after the nerve block was recorded Results: Two groups had no significant diff erence regarding baseline characteristics. A significant difference was found at T۴ about VAS (P=۰.۰۰۵). The amount of pethidine consumption was lower in the DEX group but not statistically significant except for T۴ (P=۰.۰۰۶). The two groups showed no diff erence regarding side effects such as PONV Conclusion: Injection of dexmedetomidine in combination with bupivacaine for TAPB is an effective and safe drug for controlling pain after hernia surgery.

کلیدواژه ها:

Transversus abdominis plane block ، Bupivacaine ، Dexmedetomidine ، Inguinal hernia