Hemophagocytic lymphohistiocytosis in a patient with systemic lupus erythematous

Hemophagocytic lymphohistiocytosis (HLH), is a disorder seen more often in children and is life-threatening in terms of over- activation of macrophages, and T cells resulting in cytokine storm. HLH can be familial or secondary to infections,malignancy, immunosuppression, and autoimmune conditions, such as systemic lupus erythematosus (SLE). Here, we report a ۱۰-year old female with previously diagnosed SLE who hospitalized because of fever and pancytopenia.

کلیدواژه ها:

Systemic lupus erythematosus ، Hemophagocytic lymphohistiocytosis (HLH) ، Cytokine Storm ، pancytopenia