Vilsmeier-Haack Reaction with ۲,۳,۳-Trimethyl-۳H-benzo[g]indole and Its Conversion into ۲-(۱-aryl-۱H-pyrazol-۴-yl)-۳,۳-dimethyl-۳H-benzo[g]indoles

Vilsmeier-Haack reaction of ۲,۳,۳-trimethyl-۳H-benzo[g]indole, then aqueous basic work-up, leads to benzo[g]indol-۲-ylidene- malondialdehydes. These react with various arylhydrazines and quinolin-۲-ylhydrazine to form ۳,۳-dimethyl-۲-(۱-aryl-۱H-pyrazol-۴-yl)- ۳H-benzo[g]indoles in good yields.

کلیدواژه ها:

Vilsmeier-Haack reaction ، Formylation ، Pyrazole ، Malondialdehyde ، ۲-Quinolylhydrazine ، Arylhydrazine