A Bioinformatic Approach to scRNAseq Analysis Uncovers New Aspects of Neurophysiology

سال انتشار: 1402
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 141

فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

CMTS03_229

تاریخ نمایه سازی: 14 شهریور 1402

چکیده مقاله:

Our understanding of cellular diversity and nervous system function has been revolutionized by advances in single-cell RNA sequencing (scRNAseq) technology. In this reappraisal essay, we delve into the exercises of scRNAseq in neurophysiology, involving the identification of new cell types, the analysis of cell signaling pathways, and the study of gene statement dynamics. We also argue the bioinformatic difficulties and opportunities in scRNAseq analysis, similar to the want for grade controller and standardization forms. Likewise, we point to the integration of scRNAseq in different ways, similar to spatial transcriptomics and electrophysiology Eventually, we argue the coming directions of scRNAseq in neurophysiology, involving the eventuality for the identification of new cure marks and the evolution of individualized medicine. This review highlights the import of scRNAseq technology in advancing our understanding of the nervous system and its implicit to chip into the evolution of new remedial programs for neurological disorders

نویسندگان

Seyyed Mohammad Yaghoubi

Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran

Fatemeh Riyahi

Department of Plant, Cell and Molecular Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran

Homeira Hatami

Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran