Survey of medicine susceptibility in Brucella melitensis isolated from raw milk of sheep and goat in Kerman

Background and Aim: Brucellosis is one of the most common zoonotic disease between human and cattle breeding. Brucellosis is endemic in all regions of Iran. Since brucella is an arbitrary intracellular organism and a limited range of antibiotics are effective to it, this study is based on the survey of the antibiotic sensitivity to the ۹ isolated B.melitensis from raw milk in tribes population. Materials and Methods: Antimicrobial susceptibility of ۹ B.melitensis bacteria isolated from nomadic livestock population’s raw milk were studied in the laboratory. The minimum inhibitory concentration (MIC) of tested antimicrobial substances were measured by E- test. To interpret the results, CLSI standards were used for bacteria growth. Results and Conclusions: ۹ isolates had a high sensitivity to Doxycycline, two isolates were resistant against three antibiotics Streptomycin (MIC≥۲۴۰μg/mL) Cotrimoxazole (MIC≥۲۵۶μg/mL) and Rifampin (MIC≥۳۰μg/mL) and six other isolates were showed Intermediate and sensitivity to former antibiotics. According to results, resistance to Rifampin and Streptomycin and Cotrimoxazole were the important result of this article.

کلیدواژه ها:

Antibiotic sensitivity ، Brucella melitensis ، Raw milk ، Kerman ، حساسیت آنتی بیوتیکی ، بروسلا ملی تنسیس ، شیر خام ، کرمان