Visible-Near-Infrared Spectroscopy System for Non-Invasive Blood Glucose Monitoring

Background and aims: In recent years, diabetes is one of the most important causes of death inthe world. The main reason is an unhealthy lifestyle. In this disease, blood glucose concentrationincreases greatly, which is an important indicator in the diagnosis of diabetes. Preferably, in orderto prevent diabetes or control it, while being safe from its complications, the blood glucose levelshould be checked regularly. So far, various researches have been conducted and many productshave been distributed to the world market, which is the most reliable method of using invasiveblood glucose devices, but usually this method is associated with pain and discomfort in people.Also, this method increases the possibility of contracting infectious diseases. In the last fewdecades, researchers have sought to compare different methods of measuring blood glucose withnon-invasive methods. For this purpose various electrochemical sensors have been made, Butthese sensors have problems such as expensive materials, sensor instability and lack of calibration.As a result, they are not a good substitute for invasive blood sugar testing devices. In fact,with the aim of improving the conditions, we have designed a device that regularly monitorsblood glucose levels using a visible-near infrared optical sensor.Method: In this system, the waves used are in the range of near-infrared and visible waves witha specific wavelength, which have the highest amount of blood glucose absorption in this wavelength.According to Beer-Lambert’s law, the intensity of the light passing through the ear tissueis measured and amplified in the circuit designed in the system. Then the data (blood glucoseconcentration) is transferred to the computer by USART serial, and based on the voltage changecreated in the hardware, and as a result, the blood glucose level is calculated in the LabVIEWsoftware based on the Beer-Lambert’s law. In calculating blood glucose, parameters such as age,gender and skin color are used to measure the thickness of the ear tissue. In this project, the bloodglucose concentration of healthy people and people with diabetes was compared. To compare theresults of this research the specified tests were performed with the mentioned two non-invasivedevices and the other invasive, Care Sense N(It has FDA, ADA, CE standards)device.Results: One of the general results in this experiment is the comparison and measurement of theblood concentration of people with two invasive and non-invasive devices. This test was takenfrom Asian people(۱۰women and ۱۰men in the age range of ۲۰-۵۰ years).Each person has twoaggressive and non-aggressive blood concentration numbers. The average error percentage measuredin the non-invasive device is ۱۲%.Conclusion: Optical detection technology is more popular than other detection technology that,near-infrared spectroscopy has more potential for commercialization and general use in societydue to its cheapness and accuracy.

کلیدواژه ها:

diabetes ، spectroscopy near-infrared ، non-invasive blood glucose monitoring ، glucose concentration