Maternal Age-Related Chromosomal Aneuploidy in Human Day ۳ Embryo Biopsy Blastomeres in Couples Undergoing IVF Cycles in Kuwait

Preimplantation genetic diagnosis is recognized as an effective approach to rule out embryos with abnormal chromosomes in hopes of increasing the chances of a successful pregnancy. The objective of this study is to evaluate the association between types of single cell (blastomere) chromosomal aneuploidy and female partner age using Next Generation Sequencing technique. This study showed that ۷۰.۸۰% of tested samples had abnormal chromosomal complementation, regardless of maternal age or complexity of the abnormality present.

کلیدواژه ها:

Next Generation Sequencing ، Genetics ، Blastomeres ، Aneuploidy ، Chromosomes