Comparison Of Intracranial Blood Pressure (ICP) Monitored Versus Non Monitored Severe Traumatic Brain Injury (TBI) Patients

Background: This study aimed at comparing mortality and morbidity in TBI patients, with and without ICP monitoring. Method: This study was designed as a retrospective case-control study. The study compared mortality and morbidity (bleeding and meningitis) outcomes, length of hospitalization, and trends of Glasco coma scale changes in patients who underwent ICP monitoring (case group, n=۱۱) with non-monitored (control group, n=۱۱) patients. These subjects were matched for age and sex. Results: Groups were matched for age and demographic variables (P>۰.۰۵). However, initial GCS in case group was significantly lower than controls (P=۰.۰۰۹). So assuming that this variable is a confounding factor, other comparisons were made by adjusting the initial GCS. ICP monitoring had a statistical association with mortality (OR= ۲۲.۸۰, ۹۵% CI: ۲.۲۸-۲۲۷.۷۶; p<۰.۰۰۰۱), but not with meningitis. After adjusting for baseline GCS, there were no differences between adjusted and non-adjusted results; but small sample size restricts this statement. The adjusted means of GCS on day ۱ for case group and control group were ۹.۰۴ and ۱۲.۴۴, respectively (p=۰.۰۴۵). The adjusted means of GCS on day ۲ for case group and control group were ۱۰.۲۷ and ۱۳.۲۳, respectively (p=۰.۰۷۳). Conclusion: The retrospective case control design failed to assess the hypothesis of associations between ICP monitoring and outcomes of TBI, in our small sample size study.

کلیدواژه ها:

Mortality ، Morbidity ، TBI Patients ، With and Without ICP Monitoring