The effect of a resistance-power training and vitamin D supplementation on serum IGF-۱ concentration and physical function in elderly women

Introduction: This study was aimed to evaluate the effect of a period of resistance-power training and vitamin D supplementation on serum insulin-like growth factor ۱ (IGF-۱) concentration and physical function in elderly women.Method: ۴۴ elderly women volunteered and were randomly divided into four groups of training + placebo (TP), training + vitamin D (TS), vitamin D (vit D) and placebo (P). The training groups performed a weight training program for ۱۲ weeks (three sessions per week). People in the Vitamin D group took one ۵۰,۰۰۰ IU vitamin D jelly tablet every two weeks, and the P group took one placebo capsule (rice flour). Blood samples were taken from all subjects before and after the training and measured serum Vitamin D and IGF-۱. Physical function indices were also measured. Data were analyzed using SPSS ۲۵ and R۳.۵.۲ software, and analysis of variance of weighted repeated measures.Results: Serum vitamin D was significantly increased in TS and vit D groups compared to control group, while it was significantly decreased in TP group (p ≤ ۰.۰۵). Training and supplementation interventions had not significant effects on serum IGF-۱ (p ≥ ۰.۰۵). There was a significant increase between physical function indices in the TS and TP groups compared to the control group (p ≤ ۰.۰۵), while there was no significant difference between the two groups.Conclusion: Performing resistance-power training in the elderly improved the physical function indices; however adding vitamin D supplementation to the trainings did not had a greater effect on physical function.

کلیدواژه ها:

resistance-power training ، Vitamin D ، IGF-۱ ، physical function ، aging