A New Thermo-Responsive Hyaluronic Acid Sol-Gel to Prevent Intrauterine Adhesions after Hysteroscopic Surgery

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 156

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شناسه ملی سند علمی:

HUMS04_172

تاریخ نمایه سازی: 3 خرداد 1402

چکیده مقاله:

Introduction and objective: Intrauterine adhesion is an excessive fear after intrauterine surgical treatment, adjuvant treatments could not save you the medical symptoms and improvements pregnancy in the ones sufferers. Currently, the treatment for IUA is hysteroscopic. With this treatment method, there may be nevertheless an immoderate recurrence charge. Our goal to check effect hyaluronic acid gel to Prevent Intrauterine Adhesions after Hysteroscopic Surgery.Method: In the forthcoming systematic study, the required data were collected using keywords and citing valid databases such as: Scopus PubMed, Google Scholar and ProQuest. The statistical population of the study includes all studies conducted up to ۲۰۲۲ in the field of A New Thermo-Responsive Hyaluronic Acid Sol-Gel to Prevent Intrauterine Adhesions after Hysteroscopic Surgery. After reviewing the relevant Results and evaluating the data quality, a total of ۲۵ articles were analyzed.Result: Hyaluronic acid is a drastically polymerized chain of disaccharides and a mucopolysaccharide that has crucial physiological abilities withinside the body, collectively with of blood vessel wall permeability and electrolytes, and wound healing. Hyaluronic acid can integrate with water molecules and reason tissue hydration, due to which lower mobileular resistance to save you to mechanical damage. Due to its excessive biocompatibility and enzymatic biodegradation, it’s often used to save you tissue adhesion after surgical treatment. The recurrence charge of intrauterine adhesion after using hyaluronic acid gel become not statistically significant, but was reduced the charge of IUA. It has appreciably reduced the incidence of moderate-to-excessive IUA after using hyaluronic acid gel, but no effect on the moderate IUA. Analysis showed that intake of hyaluronic acid gel had Contradictory outcomes, had with expanded incidence of pregnancy. The drawback of the reviewed research become the shortage of placebo control.Conclusion: The use of hyaluronic acid gel after the intrauterine surgical appears to be extra useful for sufferers with excessive and intense risk of IUA. However, extra research is wanted with withinside the destiny to confirm its effectiveness and protection in protective fertility.

نویسندگان

Arezoo Kalteh

M.Sc. Student in Midwifery Counseling, student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran

Zohreh Amiri

Department of Surgical technology, School of Abarkouh Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Elika Abbaszadegan

Midwifery and Reproductive Health Department, School of Nursing and Midwifery, Iran University of Medical Science, Tehran, Iran

Zahra Sadat Yaganegan

Department of Microbiology, faculty of Biological Sciences and Technology, shahid Ashrafi Esfahani University, Isfahan, Iran

Somayeh Raeisi

Department of Midwifery Reproductive Health School of Nursing & Midwifery Iran University of Medical Sciences, Tehran, Iran

Elaheh Oliyaei

Bachelor student of radiology Faculty of Para medicine, Department of medicine, Bushehr University of Medical Science, Bushehr, Iran