Attributable fraction of tobacco smoking on selected cancer deaths in thepast decade using mortality case-control study in Isfahan, Iran

Background: This study aims to estimate the impact of smoking-attributable mortality of selectedcancers, in the period ۲۰۱۵-۲۰۲۱ in Isfahan, Iran.Methods: A case-control study was conducted to assess the smoking-attributed major causes ofcancer deaths. Unmatched multiple logistic regression was used to calculate mortality risk ratios.Results: Smoking-attributable cancer deaths were۲۵۲۴ (۲۲.۶۵%) among adult males and ۵۶۵(۶.۸۸%) among adult females in the period ۲۰۱۵-۲۰۲۱ in Isfahan, Iran. Lung cancer remains thelargest cause of smoking-attributable deaths; among men, the death rates were ۵۱.۰۷% of lungcancers, ۲۹.۵۷% of mouth, pharynx, larynx, or esophagus cancers, ۱۲.۱۸% of kidney and otherurinary cancers, and ۱۰.۱۱% of liver cancers; among women the corresponding death rates were۳۵.۶۶% of lung cancers and ۱۵.۶۱% of the mouth, pharynx, larynx, or esophagus cancer, ۱۰.۵۶%of bladder cancers. Smoking-attributed cancer deaths in men increased from ۱۱۰۲ in ۲۰۱۰ to ۲۶۹۵in ۲۰۱۹; for women, the number remained stable at just over ۷۶۳ per year during the past decade.Conclusions: At least one in three cancer deaths in men and one in six in women would bepotentially preventable through appropriate control of tobacco smoking in Isfahan, Iran. Effectivecontrol programs against tobacco smoking should be further implemented.

کلیدواژه ها:

Isfahan ، Iran ، Cancer ، Mortality Case-Control Study ، Smoking Attributed Death