The Effect of Controlled Diabetic and Non-diabetic Saliva on Candida albicans Adherence to Heat Polymerized Acrylic Resin Discs
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 151
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شناسه ملی سند علمی:
JR_JKMU-30-1_010
تاریخ نمایه سازی: 28 فروردین 1402
چکیده مقاله:
Background: Oral candidiasis is one of the most common infections in diabetic patients that may occur due to a decrease in salivary flow rate, alterations in the salivary composition, or both. This study aimed to investigate the effect of diabetic and non-diabetic saliva on Candida albicans adherence to the acrylic resin disc specimens, regardless of saliva volume.Methods: In this case-control study, the population consisted of ۲۶ subjects in ۲ groups (۱۳ diabetic patients and ۱۳ non-diabetic patients). In both groups, unstimulated whole saliva was collected. It was investigated for pH, salivary flow rate, and adhesion of C. albicans to polymethylmethacrylate disc. After preparing the polymethylmethacrylate discs, the samples were stored in diabetic saliva, non-diabetic saliva, and distilled water (negative control group) for ۶۰ minutes at ۳۷oC. Then they were immersed in the yeast suspensions containing C. albicans and stained with gram stain. Yeast cells were counted using a light microscope.Results: The pH of unstimulated whole saliva in diabetic patients was significantly lower than in the control group. There was no significant difference between the flow rates of saliva in the two groups. Findings indicated that the adhesion of C. albicans to resin in diabetic saliva was higher than in non-diabetic saliva.Conclusion: This study showed the same amount of salivary flow rate in diabetic and non-diabetic individuals, lower pH, and higher Candida adherence to heat polymerization acrylic resin in the diabetic group.
کلیدواژه ها:
نویسندگان
Samira Hajisadeghi
Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Qom University of Medical Sciences, Qom, Iran
Roohollah Fateh
Department of Microbiology and Immunology, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran
Arash Jangjoo
Department of Prosthodontics, Faculty of Dentistry, Hormozgan University of Medical Sciences, Hormozgan, Iran
Atie Behrouzirad
Department of Orthodontics, Faculty of Dentistry, Qom University of Medical Sciences, Qom, Iran