The effect of resistance training on serum levels of dehydroepiandrosterone, estradiol, and erectile dysfunction in men with type ۲ disease

Background & objectives: Diabetes through sex hormone deficiency can cause erectile dysfunction in type ۲ diabetic men, however, resistance training can improve diabetes by reducing complications of this disorder. The purpose of this study was to investigate the effect of resistance training on serum levels of dehydroepiandrosterone, estradiol and erectile dysfunction in type ۲ diabetic men.Materials and Methods: In this quasi-experimental study, ۲۴ men with type ۲ diabetes with a mean weight of ۷۷.۱±۳.۵ kg and BMI of ۲۶.۱۳±۳.۳ kg/m۲ were randomly selected. They were randomly divided into two groups Diabetics were divided into control exercises and diabetic control. The diabetic group performed ۸ weeks of resistance training with resistance training. Serum levels of dehydroepiandrosterone, estradiol, erectile dysfunction and other dependent variables were measured ۴۸ h before and after the training period. Data were analyzed using covariance analysis (ANCOVA) (P=۰.۰۵).Results: Resistance training in diabetic group resistance training significantly decreased insulin resistance index (HOMA-IR) compared to diabetic control group (P=۰.۰۱۰). Resistance training also significantly decreased serum estradiol levels (P=۰.۰۴۰) and significantly increased serum levels of dehydroepiandrosterone (P=۰.۰۳۰) in diabetic group resistance training compared to diabetic control group. Resistance training also increased erectile function in the areas of erectile function (P = ۰.۰۱۹), marital satisfaction (P=۰.۰۱۲) and total scores (P=۰.۰۰۲) in diabetic group resistance training compared to diabetic control group.Conclusion: Overall, based on our findings, it seems that resistance training reduces serum estradiol levels and increases serum levels of dehydroepiandrosterone in improving erectile function in type ۲ diabetic patients.

کلیدواژه ها:

Type ۲ diabetes ، Resistance training ، Dehydroepiandrosterone ، Estradiol ، Erectile function.